Analyse des coûts dans les programmes de soins de santé by Andrew L. Creese, David Parker

By Andrew L. Creese, David Parker

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Example text

6 Determination of the Diffusion Coefficient from Sorption or Desorption Kinetics 49 The quantity in square brackets contains only the constant π , and can be evaluated. 049 D= .

21) where numerical suffixes denote times (t). 21) Vreceiver dCreceiver dCdonor = −Vdonor = F = PA (Cdonor − Creceiver ) . 22) The integral solution can be expressed as −PA 1 Vdonor + 1 Vreceiver t = ln Cdonor − Creceiver . 23) assumes more convenient forms under the following situations. If Cdonor is held constant by having Vdonor Vreceiver or by other means, Vdonor becomes unimportant and we can write −PAt C0 − Creceiver = ln . Vreceiver C0 If Creceiver is held zero or nearly so by having Vreceiver −PAt Cdonor = ln .

2, but in this case we would not know if P is constant or if it depends on concentration. In this model, the thickness of the membrane need not be known. 0 0 1 2 3 4 Donor concentration (10−3 mol/m3) 5 6 Fig. 3 The effect of donor concentration on steady state flux of urea Hence, model 1 is suitable in all cases when membrane thickness is not known or difficult to estimate accurately. 2 Model 2 We next want to find out how the flux varies when we change membrane thickness ( ). With biological membranes thickness cannot be manipulated, but for the present purpose we use a gelatine membrane which can be prepared at different thicknesses by casting 10% hot aqueous gelatine between two glass plates separated by spacers.

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